Viagra information

Viagra New ZealandViagra (Sildenafil) is perhaps the most widely known and popular drug that is utilized as medication therapy for erectile dysfunction in men. However, this is not the only indication for this medication. It is also sometimes recommended off-label to women who suffer from low libido and sexual disorders due to its pronounced abilities to dilate the blood vessels, and also in cases where a dilation of the blood vessels in the lungs would be beneficial, such as in pulmonary hypertension. Viagra may be combined with drugs for premature ejaculation, such as Dapoxetine, or may be used as a standalone therapeutical remedy for erectile dysfunction. Sildenafil is the ingredient that makes Viagra work so effectively, and it is a pharmaceutical remedy that is categorized as a phosphodiesterase type 5 inhibitor, also called PDE5 inhibitor. While Viagra is the most well known representative of the PDE5 inhibitor medication category, other drugs like Tadalafil, Avanafil or Vardenafil are also available. However, Sildenafil formulated as Viagra remains the first choice for many individuals since it is the classical prototype for this kind of drugs combatting ED symptoms.

How does Viagra (Sildenafil) achieve its effects in terms of diminishing or curing erectile dysfunction in male individuals?

The main effects of Viagra revolve around its potent capacity to dilate the blood vessels in the penis, and specifically in highly specialized structures entitled the cavernous bodies. How is Viagra able to influence the blood vessels on a biochemical level and stimulate a healthy erection in an individual with ED symptoms? Sexual arousal in men is typically followed by a signal transmitted from the specific region of the brain that responds to sexual-related stimulation, and the nerves in the penis respond by releasing nitric oxide (NO). The nitric oxide is used for “communication” purposes because it signals to an enzyme the need to produce more cyclic GMP, which is the central chemical component in the physiological erectile response. The produced cGMP directly dilates the modified blood vessels in the cavernous bodies, which are now becoming filled with blood and the erection occurs. This cascade of events results in the facilitation of a normal, healthy sexual act. The PDE5 enzyme is able to destroy a certain amount of the produced cGMP, which may diminish the erectile potential in some men. Viagra works by blocking this enzyme, and therefore promotes higher cGMP levels and a strong response involving an erection. Viagra (Sildenafil) has been tested for side effects and safety, and it successfully passed all trials with very few potential adverse effects that may be experienced by very few of men, including temporary headaches, nausea or nasal congestion. Use Viagra only with your physician’s approval.