Levitra, also known as Vardenafil, is a drug that is used mainly in the treatment of erectile dysfunction, but also other disorders. Together with Tadalafil and Sildenafil, Levitra belongs to the class of medication called phosphodiesterase type 5 inhibitors, or simply PDE5 inhibitors. These drugs have a potent effect of dilating the blood vessels in the penis, which leads to an erection, especially in men who have trouble initiating and maintaining a normal sexual intercourse.
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How Levitra works
Levitra works by inhibiting an enzyme, which is PDE5, when it participates in a series of events that form the mechanism of a normal erection. When sexual stimulation occurs, the nerves that supply the cavernous bodies of the penis release transmitter molecules called nitric oxide, or simply NO. This signaling agent stimulates an enzyme that starts the production of an active compound called cGMP. This biologically active molecule directly acts on the blood vessels located in the penis, which causes their dilation and leads to an erection. However, the duration of action of cGMP is shortened by the intervention of PDE5, which is an enzyme that destroys cGMP and thus terminates its action. This mechanism is especially prominent in men who suffer from erectile dysfunction.
High Effectiveness up to 6 hours
Levitra has the capacity to help men who suffer from erectile dysfunction by inhibiting PDE5, which leads to more cGMP being available for a potent erection. This is how Levitra directly improves the strength of the erection and its duration, enabling a normal sexual intercourse for men who suffer from ED. The duration of action of Levitra is several hours, and it typically ranges from 4 to 6 hours. Levitra is also successfully used in certain cases of premature ejaculation because of its ability to prolong the interval from the penetration of the vagina to ejaculation. There also have been several clinical studies that revealed that PDE5 inhibitors, including Levitra, may be effective in certain sexual disorders for women because of their ability to increase the blood flow in the pelvic region, which is where the genital organs are located.
Possible side effects
Although Levitra is safe and effective in the therapy of erectile dysfunction and premature ejaculation, it is best to take it after consulting your doctor, who may make the necessary dosage adjustments and monitor any potential side effects. Levitra is usually associated with very few and mild side effects.
“Levitra side effects may include nausea, headaches, facial swelling, abdominal disturbances, low blood pressure and sensitivity to light. If other side effects are present during treatment with Levitra, don’t hesitate to inform your doctor to benefit from a safe and effective treatment regimen.”
Dr. J C Powell, Auckland